Catalyst Loading Controls Chemoselectivity: Unusual Effect in Rhodium(II) Carbene Insertion Reactions with Tetrahydrofuran
نویسندگان
چکیده
(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones previously shown to yield two products in reactions with tetrahydrofuran mediated by rhodium carbenes—tetrahydrofur-2-yl-substituted product of C-H insertion and spirocyclic formal C-O insertion. Accidentally, it was noted that the ratio depends on catalyst loading, phenomenon investigated detail. It found be preparative significance: solely changing loading from 0.01 mol% 10 mol%, one can obtain sound yields either products. Mechanistic kinetic interpretation this new has been proposed.
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ژورنال
عنوان ژورنال: Catalysts
سال: 2023
ISSN: ['2073-4344']
DOI: https://doi.org/10.3390/catal13020428